Dynamic concentration of motors in microtubule arrays.
نویسندگان
چکیده
We present experimental and theoretical studies of the dynamics of molecular motors in microtubule arrays and asters. By solving a convection-diffusion equation we find that the density profile of motors in a two-dimensional aster is characterized by continuously varying exponents. Simulations are used to verify the assumptions of the continuum model. We observe the concentration profiles of kinesin moving in quasi-two-dimensional artificial asters by fluorescent microscopy and compare with our theoretical results.
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ورودعنوان ژورنال:
- Physical review letters
دوره 86 14 شماره
صفحات -
تاریخ انتشار 2001